Every cardiovascular clinical trial that has examined the beneficial effects of lowering LDL cholesterol to prevent cardiovascular events has demonstrated residual cardiovascular risk in the interventional treatment group. Residual risk is the term applied to the cardiovascular events e.g. myocardial infarction stroke and cardiovascular death that occur in spite of being on
n engl j med 3745 nejmFebruary 4 2016 425 Minimal Residual Disease in Standard Risk AML ABL1 cycle threshold values of 30 or more were excluded from the
It has the implication that an intervention such as lipid lowering which reduces acute event rates probably in large part due to stabilising the plaque and reducing the risk of clinically expressed disruption would also reduce the risk of subclinical events and thereby slow angiographic progression. Angiographic progression and the risk of
Oct 20 2021 Thus the identification of a new specific condition associated with higher CHD risk and disease progression not tackled by current treatments is a relevant unmet need 17.
Moise A. Theroux P. Taeymans Y. et al. Clinical and angiographic factors associated with progression of coronary artery disease . J Am Coll Cardiol 1984
Thinking outside the lumen fractional flow reserve versus intravascular imaging for major adverse cardiac event prediction
treated with ACE inhibitors or ARBs their residual risk of adverse renal and cardiovascular outcomes remains higher than that in age matched and sex matched counterparts without diabetes 4 5 and diabetes remains the leading cause of end stage renal disease in most parts of the world.6 7 Novel treatments are therefore needed to
Both regimens had striking effects on coronary disease progression resulting in significant regression of atherosclerosis. These data indicate that
Mar 09 2019 The prevalence of asymptomatic coronary artery disease CAD in type 2 diabetes T2D is unclear. We investigated the extent and prevalence of asymptomatic CAD in T2D patients by utilizing invasive coronary angiography ICA and intravascular ultrasound IVUS and whether CAD progression evaluated by ICA could be modulated with a multi intervention to
Backgrounds A plug and play standardized algorithm to identify the ischemic risk in patients with coronary artery disease CAD undergoing percutaneous coronary intervention PCI could play a valuable step to help a wide spectrum of clinic workers. This study intended to investigate the ability to use the accumulation of multiple clinical routine risk scores to predict long term
Factors Associated With Coronary Artery Disease Progression Assessed By Serial Coronary Computed Tomography Angiography. Arquivos Brasileiros de Cardiologia Jan 2017 Gabriel Cordeiro Camargo Tamara Rothstein Maria Eduarda Derenne Leticia Sabioni João A. C. Lima Ronaldo de Souza Leão Lima Ilan Gottlieb
Aug 25 2021 1. INTRODUCTION. Coronary artery disease CAD is still a major cause of death worldwide. Despite great advances in its diagnosis treatment and prevention adverse cardiovascular events do not seem to decline on the background of optimal medical therapy. 1 The importance of identifying residual risk and screening the coronary atherosclerotic
This risk becomes evident in the study at anHbA1clevel of below 5.9 pre diabetes which showed pre diabetics should strictly control blood sugar a slight increase in HbA1c can lead to serious progression of coronary heart disease. This risk reduced at an HbA1clevel of above 5.9 it may be due to the application of cardiovascular related
Feb 18 2015 the role of clinical and angiographic scores to determine the mode of revascularization in patients with stable coronary artery disease Although he indiceted some progression of symptoms it was difficult to confirm by clinical history. and for those with high–risk anatomy left main disease or equivalent three vessel disease or
Oct 03 2021 Quantitative assessment of residual disease using the RCB method was generalizable across a network of clinical trial sites and provided prognostic information in all subtypes of breast cancer. Prognostic surrogacy of RCB was irrespective of neoadjuvant treatment and provides an assessment of residual risk that appears to be clinically
Angiographic Features of Intracranial Aneurysms in Ecuador. Association Between Triglycerides and Residual Cardiovascular Risk in Patients With Type 2 Diabetes Mellitus and Established Cardiovascular Disease From the Bypass Angioplasty Revascularization Investigation 2 Diabetes BARI 2D Trial . Association of Disease Progression With
Evidence on the natural angiographic course of moyamoya disease MMD is lacking. It takes about 6 months for waiting for revascularisation surgery. The issue of when to perform subtraction angiography DSA for follow up remains unclear. We investigated the natural course of MMD by DSA and attempted to determine the best interval to perform the follow up DSA. This is a
Jan 06 2020 Residual risk targeting triglycerides and Lp a 07 09 Educational information This video was recorded as part of the two day meeting Current Challenges in Lipid Management and Cardiovascular Risk Reduction at Brigham and Women s Hospital/Harvard Medical School in Boston MA USA on October 31 2019.
Aug 18 2020 Objective Patients with CAD have substantial residual risk of mortality and whether hitherto unknown small molecule metabolites and metabolic pathways contribute to this risk is unclear. We sought to determine the predictive value of plasma metabolomic profiling in patients with CAD. Approach and results Untargeted high resolution plasma metabolomic
Feb 20 2013 Arterial elasticity has been shown to predict cardiovascular disease CVD in apparently healthy populations. The present study aimed to explore whether arterial elasticity could predict CVD events in Chinese patients with angiographic coronary artery disease CAD . Arterial elasticity of 365 patients with angiographic CAD was measured.
Jan 03 2020 Aim . Optimal revascularization strategy in multivessel MV coronary artery disease CAD eligible for percutaneous management PCI and surgery remains unresolved. We evaluated in a randomized clinical trial residual myocardial ischemia RI and clinical outcomes of MV CAD revascularization using coronary artery bypass grafting CABG hybrid coronary
Angiographic Disease Progression and Residual Risk of Cardiovascular Events While on Optimal Medical Therapy Observations From the COURAGE Trial November 2011 Circulation Cardiovascular
Sep 25 2020 Detecting residual cardiovascular risk using coronary CT angiography 10 educationOct. 18 2021Prof. Charalambos Antoniades MD PhD. Atrial fibrillation. LDL c lowering treatment impacts disease progression before clinical manifestation LDL c Key Lessons. Lipids.
May 07 2020 Chronic kidney disease CKD is a growing public health problem that is driven by an ageing population and the obesity epidemic .The hallmark of CKD is low estimated glomerular filtration rate eGFR but albuminuria also increases the risk of CKD and progression to end stage kidney disease ESKD especially among patients with diabetes 3 4 5 .
Nov 19 2019 1 INTRODUCTION. Residual cardiovascular CV risk in statin treated patients persists despite control of LDL cholesterol. 1 Other atherogenic lipids and lipoproteins such as triglycerides TGs and TG rich lipoproteins TRLs are also likely causal and prognostic factors as well as potential treatment targets in atherosclerotic CV disease ASCVD . 1 2 The